Welcome to the Cho Lab!
Welcome to the Laboratory of Veterinary Biochemistry at Seoul National University!
Our laboratory investigates cancer in companion animals and humans through the lens of comparative medicine. Building on the Comparative-medicine Disease Research Center (CDRC), selected as a Science Research Center (SRC) by the Ministry of Science and ICT in 2021, we focus on naturally occurring human breast cancer and canine mammary tumors to uncover shared mechanisms of tumorigenesis and species-specific differences, and to translate these findings into new diagnostic and therapeutic strategies.
We focus on several fundamental questions:
1. What molecular and immunological features are shared between cancers in humans and companion animals?
2. How do immune cells and cancer cells interact within the tumor microenvironment?
3. Why do some immune responses successfully control cancer, whereas others fail?
4. How can we optimize immune cell function to promote more effective anti-tumor responses?
To address these questions, our laboratory integrates a range of advanced research approaches, including comparative genomics, comparative epigenomics, the development of companion animal-derived organoid and assembloid models, and tumor microenvironment analysis.
Through comparative medicine, our lab seeks to uncover new insights and develop therapeutic approaches that improve health outcomes for both animals and humans.
Je-Yoel Cho, DVM, Ph.D.
Professor, Department of Biochemistry, College of Veterinary Medicine, Seoul National University
Director, Comparative-medicine Disease Research Center (CDRC/SRC)
Je-Yoel Cho, DVM, Ph.D.
Professor
Department of Biochemistry, College of Veterinary Medicine
Seoul National University
CDRC (SRC) Director
Rm 811, 1-Gwanak-ro, Gwanak-gu
Seoul, 08826, South Korea
Email: jeycho@snu.ac.kr
Academic Career
1985 – 1989 : D.V.M., Seoul National University, S. Korea
1989 – 1991 : M.S., Veterinary Physiology, Seoul National University, S. Korea
1993 – 1995 : M.S., Physiology & Cell Biology, The Ohio State University, Columbus, OH
1995 – 1999 : Ph.D., Physiology & Cell Biology, The Ohio State University, Columbus, OH
Work Experience
1999.07 – 2000.12: Postdoctoral Research Fellow, Department of Physiology & Cell Biology,
The Ohio State University, Columbus, OH
2001.01 – 2003.08: Postdoctoral Research Fellow in BIDMC Genomics Center,
Harvard Medical School, Boston MA
2003.09 – 2011.08: Lecturer, Assistant and Associate Professor, Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu, South Korea
2011.09 – 2015.02: Associate Professor, Department of Biochemistry, College of Veterinary
Medicine, Seoul National University
2015.03 – Current: Professor, Department of Biochemistry, College of Veterinary
Medicine, Seoul National University
2016.07 – 2019.01: Dean of SNU Gwanak Residence Halls, Seoul National University
2019.03 – 2021.02: Associate dean of academic affairs, College of Veterinary Medicine, Seoul National University
2025.02 – 2027.01: Dean, College of Veterinary Medicine, Seoul National University
Commissions of Trust and Editorial Boards
2008-2009: Secretary of Planning of Korean Human Proteome Society
2009: Secretary General of Advanced Medical Biomarker Council
2009: Secretary of Public Relations of KSBMB
2010-2011: Secretary of Academic Affairs of KHUPO
2012-2013: Secretary General of KHUPO
2013-2014: Committees of KSBMB Winter Conference
2015-2016: Committee Chair of KSBMB Winter Conference
2014-2015: Co-Director, the External Relations Committee of KSSCR
2014-2018: Vice President of Korean Human Proteome Society
2014-2025: Council member of Asia Oceania Human Proteome Organization (AOHUPO)
2013- 2015: Editorial board, Cancer Research
2009- Current: Editor-in-Chief, The Open Biochemistry Journal
2018-2021: President of Korean Human Proteome Society (KHUPO)
2017-2020: Council member of Human Proteome Organization
2020-2021: AOHUPO 2021 Organizing Committee Chair
2018-2020: Editorial board, Proteome Science
2019- Current: Editorial board, Scientific Reports
2021- Current: Associate Editor, Proteome Science
2021-2028: Director of Comparative Disease Research Center (CDRC) SRC
2022-2024: Council member of Human Proteome Organization (HUPO)
2023: Congress Chair of HUPO 2023, Busan